The Brain Chemistry Labs Approach

As a not-for-profit organization headquartered in Jackson Hole, Wyoming, our mission is to discover new cures from plants. With a state-of-the art laboratory in Jackson, we have assembled a team of researchers who are working tirelessly to find and fight causes of disease and to search for new cures from plants.

Current projects of the Institute include:

  • Development of L-serine as a possible new drug for ALS; » More

  • Development of Prostratin as a new drug for HIV/AIDS; » More

  • Studying cyanobacterial toxins throughout the world. » More

Our studies of remote Pacific island villages with high incidence of ALS led to reconsideration of BMAA—a toxic amino acid—as a possible trigger for certain neurodegenerative illnesses in genetically vulnerable individuals. We and our collaborators have found that BMAA is produced by cyanobacteria which occur throughout the world.

We have developed techniques to detect BMAA at extremely low concentrations in water supplies and human tissues.  Our new research demonstrates that BMAA causes brain tangles and β-amyloid deposits in the brain, two features that are diagnostic of Alzheimer’s disease and present in several other neurodegenerative diseases.  Our focus, thus far, has been on sporadic ALS and if BMAA also serves as an environmental trigger for ALS, our research will help identify those individuals who are vulnerable to the cyanobacterial toxin.  We also are exploring new approaches to ALS therapy based on BMAA research.

What makes our research approach unique?

Originally conceived on July 4, 2004, Brain Chemistry Labs officially opened its laboratories in June 2006. Patterned after the Miller Research Institute at UC Berkeley and the Institute for Advanced Studies at Princeton, Brain Chemistry Labs is an innovative research organization designed to rapidly discover new cures for serious illnesses.

Brain Chemistry Labs uses a novel model for drug discovery that is significantly different from the traditional pharmaceutical company. Rather than investing in brick and mortar and establishing a large, bureaucratic organization, Brain Chemistry Labs has created a virtual model by inviting world leaders in the appropriate disciplines to perform key components of our research. This collaboration is not only unique, but very efficient and effective in rapidly advancing the research unencumbered by bureaucracy. It incorporates an innovative blend of novel discovery, exceptional human capital, and a singular mission to move from cause to cure.

Our International Consortium of Scientists

Key to innovation and discovery at the Brain Chemistry Labs is our 50 scientist consortium. Top scientists from 28 universities in 12 countries have been recruited to collaborate in our research. They are world leaders in a variety of disciplines including ethnobotany, neurology, physiology, epidemiology, oceanography, neuroanatomy, molecular biology, inorganic chemistry, physics, microbiology, ecology, and synthetic chemistry.

Members of the Brain Chemistry Labs International Research Consortium

Members of the Brain Chemistry Labs International Research Consortium